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    Prof. Surya K. Ghosh

    Assistant Professor

    Department of Physics

    National Institute of Technology, Warangal - 506004, Telangana, INDIA

    : skghosh [a] nitw [dot] ac [dot] in : 98-2070-2782

    Research Interest: Our research interest focuses on addressing problems in the interface of Physics and Biology by developing computational and statistical mechanics models. We use computer simulation to address a wide range of interdisciplinary problems, in close collaboration with experimental Physicists and Biologists. Some specific topics of interest are as follows: (i) Diffusion in crowded, confined environments, (ii) Statistical physics of biopolymers: shapes, dynamics, and translocation of model polymers, (iii) Effect of crowding on the configurations of DNA, (iv) 2D polymer network as a model for the hydrogel, (V) Kinetics of Drug Delivery. 

     

    Web-Link: https://physicsurya.wixsite.com/suryakghosh

     

    Positions:

    1. Assistant Professor, NIT Warangal ( Nov 2019 - till date)
    2. Assistant Professor, SRM University (2018 - 2019)
    3. Post Doc, CNRS, University of Grenoble, France (2016 - 2018)
    4. Post Doc, Ecole Polytechnique, University of Paris Saclay, France (2014 - 2016)
    5. Post Doc, University of Potsdam, Germany (2013 - 2014)

     

    Academic Background:

    1. PhD (Physics), IIT Bombay, 2013
    2. MSc (Physics), IIT Bombay, 2007
    3. BSc (Physics), R K Mission Belur Math, Calcutta University, 2005

     

    Collaborations: 

    • Microsoft Research, Fluid Numerics Group, USA
    • Dr. Jaeoh Shin, Rice University, USA
    • Dr. Kulveer Singh, Dept of Physics,  Bar Ilan University, Israel
    • Dr. Andrey Cherstvy, Dept of Physics, University of Potsdam, Germany
    • Dr. Thyageshwar Chandran, Dept of Biotech, NIT-Warangal, India
    • Dr. Amit Ranjan Maity, Ramalingaswami Fellow, Amity Kolkata, India
    • Dr. Mantu Santra, Dept of Chemistry, IIT Goa, India

       

    Editorial Assignment:  Associate Editor in Soft Matter Section, Frontiers in Physics, 2022 - till date

     

    Reviewer:  Phys. Rev. Lett. (PRL), Nano Letter (ACS), Phys. Rev. E. (PRE), Phys. Rev. Research (PRR), Nature Scientific Report, Biophysical Journal, Physical Biology, J. Phys. Condens. Matter, BioMed Res Int.

     

    Key Words: Computational Modelling, Langevin Dynamics, Molecular Dynamics, Monte Carlo, LAMMPS, Computer Simulation, Polymer Physics, Active Matter, Anomalous Diffusion, Macromolecular Crowding, Drug Delivery

    Course Taught Previously
    • MSc      : PH5101 -  Mathematical Physics                  (Odd 2023, 2022, 2021, 2020)
    • MSc      : PH5155 -  Computer Programming               (Odd 2023, 2022, Even 2021, 2020)
    • BTech   : PH101   -  Physics                                         (Even 2023, 2022, 2021, 2020)
    • BSc      : PHI151   -  Heat and Thermodynamics          (Even 2023, 2022)
    • MSc      : PH5155  -  Lab Computer Programming        (Odd 2023, 2022, Even 2021, 2020)
    • BTech  : PH101     -  Lab Physics                                  (Even 2023, 2022, 2021, 2020)
    • BSc      : PHI151    -  Lab Heat and Thermodynamics   (Even 2023, 2022)
    • MSc      : PH5251   -  Lab Solid State Physics                (Even 2022)

     

     

    Publications

    Selected Publications:

    • Dynamics of interior loop formation in polymer chains: effect of tail length and confinement
      • Vrinda Garg, Rejoy Mathew, Jaeoh Shin, Surya K. Ghosh*, (2023)
    • Crowding-induced switching of polymer translocation by the amalgamation of entropy and interaction
      • Vrinda Garg, Rejoy Mathew, Surya K. Ghosh*, (2023)
    • Acidic pH-Triggered Release Of Doxorubicin From Ligand-Decorated Polymeric Micelle Potentiates Efficacy Against Cancer Cells
      • S M Roy, S Barman, Pousali Bag, T Ghatak,  A Basu, Surya K. Ghosh, D Anjaneyulu, Ali Khan, S Dastidar, A R Maity
      • ACS Applied Nano Materials, 6, 18, (2023), IF: 6.2
    • Choline-based deep eutectic solvent for denitrogenation of liquid fuel: A molecular dynamics study
      • Kishant Kumar, Anand Bharti, Ajay Kumar, Surya K. Ghosh, Amit Kumar
      • Journal of Molecular Liquids, 382, 121862, (2023), IF: 6.6
    • Overcoming the barriers of nuclear-targeted drug delivery using nanomedicine-based strategies for enhanced anticancer therapy
      • S. M. Roy, Vrinda Garg, Pousali Bag, C. Ghosh, Arnab Basu, Anjaneyulu Dirisala, A R Maity, Surya K. Ghosh*
      • Journal of Drug Delivery Science and Technology, 71, 103303, (2023), IF: 5.1
    • Insights into the microevolution of SARS-ACE2 interactions: in silico analysis of glycosylation and SNP pattern
      • Pavan K Madasu, Arpita Maity, Surya K. Ghosh, Thyageshwar Chandran
      • Journal of Biomolecular Structure and Dynamics (Rapid Communication), 18, 4, (2022), IF: 5.2
    • Amine as a bottom-line functionality on DDS surface for efficient endosomal escape and enhanced subcellular targets
      • S. M. Roy, Sourav Barman, Surya K. Ghosh, Subrata Pore, Arnab Basu, R. Mukherjee, A. R. Maity
      • Journal of Drug Delivery Science and Technology, 71, 103303, (2022), IF: 5.1
    • Kinetics of nanomedicine in tumor spheroid as a model system for efficient tumor-targeted drug delivery with insights from mathematical modeling
      • Vrinda Garg, Sayoni Mitra Roy, Sourav Barman, Amit Ranjan Maity, Surya K. Ghosh*
      • Frontiers in Bioengineering and Biotechnology, 9, 7859371-31, (2021), IF: 6.1
    • Genome organization via loop extrusion, insights from polymer physics models 
      • Surya K Ghosh and Daniel Jost
      • Briefings in Functional Genomics, Oxford, 19 (2), 119-127 (2020), IF: 4.8
    • How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes
      • Surya K. Ghosh* and Daniel Jost
      • PLoS Comput Biol, 14(5), e1006159 (2018), IF: 4.7
    • Anomalous, non-Gaussian tracer diffusion in crowded two-dimensional environments
      • Surya K. Ghosh, A. G. Cherstvy, Denis Grebenkov, R. Metzler
      • New J. Phys., 18, 013027 (2016), IF: 3.7
    • Interactions of rod-like particles on responsive elastic sheets
      • Surya K. Ghosh, Andrey Cherstvy, Eugene P. Petrov, Ralf Metzler
      • Soft Matter, 12, 7908 (2016), IF: 3.6
      • – Cover: It has been featured on the front cover page of the Soft Matter journal.
      • –  Highlight: Selected in the August 7th, 2016 online issue of Assembly Papers.
    • Non-universal tracer diffusion in crowded media of non-inert obstacles
      • Surya K. Ghosh, Andrey G. Cherstvy, Ralf Metzler
      • Phys. Chem. Chem. Phys., 17, 1847 (2015), IF: 4.1
    • Deformation propagation in responsive polymer network films
      • Surya K. Ghosh, Andrey G. Cherstvy, Ralf Metzler
      • J. Chem. Phys., 141, 074903 (2014), IF: 3.5
    • Stretching force-dependent transition in single-strand DNA 
      • Kulveer Singh, Surya K. Ghosh, Sanjay Kumar, Anirban Sain
      • Europhys. Lett., 100, 68004 (2012), IF: 2.1
    • From chemosensing in microorganisms to practical biosensors
      • Surya K. Ghosh, Tapanendu Kundu, Anirban Sain
      • Phys. Rev. E., 86, 051910 (2012), IF: 2.7
    • Effect of intrinsic curvature on semiflexible polymers
      • Surya K. Ghosh, Kulveer Singh, Anirban Sain
      • Phys. Rev. E., 80, 051904 (2009), IF: 2.7
      • – Highlight: Selected for the Nov 15th, 2009 issue of Virtual Journal of Biological Physics. 

     

    PHDs Supervised
    • Vrinda Garg    (PhD, 3rd Year, JRF, DST-SERB-SRG)
    • Babu Rao        (PhD, 2nd Year)
    • Rahul Bag       (PhD, 1st Year)
    • Raman             (BSc-MSc)
    • Mehul Mishra  (BSc-MSc)

     

    • Alumni
      • Rejoy Mathew (PhD, University of Massachusetts, USA)
      • Kunal Rai        (PhD, IIT Hyderabad, India)
      • Riyan Ibrahim  (R&D, Unominda, India)

    Workshops/Conferences

    Scientific Talk:

    • Modeling Soft Matter and Biophysical Systems
      • Department of Physics and Department of Mathematics, NIT-Calicut, January 2022
    • Fundamentals of Statistical Thermodynamics
      • FDP-Recent Trends in Computer Simulations for Applications in Biotechnology, Dept of Biotech, NIT-Warangal, Aug 2020
    • Polymer Models for Chromosomes
      • Chennai, India, EESTER-2018, IIT Madras & SRM-IST,  Sept 2018
    • Effect of  Epigenetics on Chromosome Structure and Dynamics
      • Nice, France, Conference on “Computational Principles to Organize Complexity”, June 2018
    • How to build an efficient coarse-grain model for chromosomes?
      • Millau, France, GDR-ADN, April 2018
    • Chromosome in 3D!
      • Paris, France, “Conference on Nuclear Architecture”, March 2017
    • Effect of extrusion on the homopolymer model of chromosomes
      • Lyon, France, Ecole Normal Superior (ENS), March 2017
    • How to build a generic polymer model for chromosomes
      • Grenoble, France, University of Grenoble Alpes, November 2015
    • Single-molecule diffusion in a crowded environment
      • Berlin, Germany, Helmholtz-Zentrum Berlin, July 2015
    • Non-universal tracer diffusion in heterogeneous media
      • Paris, France, Paris Statistical Physics Meet, January 2015
    • How deformation propagates on hydrogel?
      • Potsdam, Germany, Potsdam Colloquium on Bioanalysis, November 2013
    • Effect of intrinsic curvature on semiflexible polymers
      • Chennai, India, Indian Institute of Mathematical Sciences (IMSc), April 2010
    • Loop Formation Probability of Intrinsically Curved Polymers
      • Mumbai, India, Tata Institute of Fundamental Research (TIFR), June 2009
    • Statistical Properties of Intrinsically Curved Polymers
      • Trieste, Italy, International Center for Theoretical Physics (ICTP), September 2008

     

    Projects

    Externally Funded Projects:

    • Role: Principal Investigator
      Funding:  MATRICS (DST-SERB)
      Title:  Statistical Physics of Crowded Environments Exhibiting Anomalous Super-diffusion 
      Fund:  ~  660000 INR
      Duration: 2023-2026 (3-years)
       
    • Role: Principal Investigator
      Funding:  SRG (DST-SERB)
      Title:  Dynamics of Complex Systems: from single particle to giant polymers 
      Fund:  ~  1700000 INR
      Duration: 2020-2023 (2-Years)

       

    • Role: Co-Principal Investigator, PI:  Dr. Mukul Pradhan, Department of Chemistry, NITW
      Funding:  DRDO
      Title:  Sunlight-mediated conversion of plastic/bio-waste to heteroatom doped graphene-based hybrid materials 
      Fund:  ~ 7200000 INR
      Duration: 2024-2027 (3 years)
       
       
    • Role: Co-Principal Investigator, PI:  Dr. Thyageshwar Chandran, Department of Biotechnology, NITW
      Funding:  Extreme Science and Engineering Discovery Environment (XSEDE), USA &  Microsoft Azure, USA
      Title:  Computational structure-based drug design 
      Fund: 50000 USD $ (approx ~ 4000000 INR )
       
    Internally Funded Projects:
    • Role: Principal Investigator
      Funding:  RSM NITW
      Title:  Study of translocation, interloop formation in polymer inside crowded environment 
      Fund:  ~  500000 INR
      Duration: 2020-2022 (2-years)

       

    Awards and Honors
    • Exceptional Reviewer: Award from the Institute of Physics (IOP), UK, in recognition of exceptionally high level of peer review competency. 2023
    • Associate Editor: Soft Matter section in Frontiers in Physics, 2022 - to date
    • Lifetime Access: to AMBER software, Rutgers University, USA, 2021
    • International Travel Grant: University of Pisa, Italy, 2018
    • Front Cover: Our work is featured on the front cover of Soft Matter RSC Journal, 2016
    • Highlight: Selected for the online issues of Assembly Papers, 2016
    • Young Researcher: Shortlisted for training on HiC data, University of Paris, France, 2017
    • Guest Scientist: Max Plank Institute, Dresden, Germany, 2011
    • Visiting Researcher: IMSc, Chennai, India, 2010
    • Best Poster Award: IIT Guwahati, 2009
    • Best Poster Award: ICTP, Trieste, Italy, 2009
    • Highlight: Selected for the Virtual Journal of Biological Physics, 2009
    • All India Rank: 88 for IIT-JAM for MSc Physics

       

    Additional Responsibility
    • Integrated MSc Coordinator, Department of Physics, NITW
    • Time Table Coordinator, Department of Physics, NITW
    • Hostel Warden, NITW
    • IISER Kolkata: External expert of the selection committee for Postdoctoral Fellows, 2022
    • Amity University: External expert of the selection committee for Ph.D. 2021- till date
    • Associate Editor: Soft Matter section in Frontiers in Physics, 2022 - till date